This AIFS report provides a comprehensive, analytical discussion of self-harm and suicidal behaviour of young people among a particular cohort in Australia. It explores the prevalence rates of self-harm and suicidal behaviour among 14–15 year olds, the risk factors associated with self-harm and the extent to which poor socio-emotional health earlier in life is associated with self-harm and suicidal behaviour. The findings highlight that interventions and preventive strategies should take place at both individual and school levels, particularly identifying those who are more likely to attempt suicide.